CBD vs THC – The Tale Of Two Cannabinoids


CBD vs THC – The Tale Of Two Cannabinoids With Very Different Jobs

Newcomers to CBD usually have a lot of questions. They often want to know if CBD will make them feel high. They also wonder if CBD shows up on a drug test. Additionally, they may not know why CBD works at all and feel skeptical about the wellness claims all over the media.

This article addresses those concerns and more. It’s also a nice overview on the ECS, how CBD works, and how it’s different from its sibling, THC.

CBD vs THC: THC And CBD Are Cannabinoids

Cannabinoids are organic compounds. Hemp and cannabis produce these compounds in their reproductive system. Once created, cannabinoids help the plant defend itself from physical and environmental threats.

Because all vertebrates possess something called an Endocannabinoid System (ECS), these substances also produce effects when we ingest them. They enter the body and bind to receptors in this system, originally created to bind with the few endocannabinoids our bodies naturally produce. Next, they influence cellular communication and the levels of enzymes that interact with endocannabinoids.

It isn’t essential to understand exactly how all this works, but this is what is happening behind the scenes. For more detailed information, Project CBD is an excellent resource.

The appreciable effects this activity produces include improvement in mood, reduction in pain, inflammation and seizures, and improvement in sleep quality.

CBD vs THC: Does CBD Make You Feel High?

CBD does not make you feel high and the reason is quite simple and completely reliable. While THC binds with CB1 receptors located in the brain and CNS, CBD influences CB2 receptors. These different receptors are located in the immune system and related areas in the body.

THC causes intoxication because it impacts areas of the brain that affect coordination, cognition, and memory. CBD interacts with totally different receptors which have no effect on your dexterity or perception of your surroundings. Instead, it largely affects pain and inflammation.

Whether CBD actually binds to these receptors or simply alters the levels of endocannabinoids that do, it has no effect on areas of the body that produce intoxication.

CBD vs THC: Does CBD Show Up On A Drug Test?

CBD use does not show up on most types of drug tests. General drug screenings are looking for certain byproducts that THC creates in the body as it breaks down. CBD simply does not produce these byproducts.

Therefore, your CBD use can be as discreet as you want.

CBD vs THC: Why Does CBD Work?

Science used to understand that CBD attached to CB2 receptors the way THC does with CB1. The current opinion on this, however, is clearly stated by Project CBD:

Although CBD has little binding affinity for either of the two cannabinoid receptors (CB1 and CB2), cannabidiol modulates several non-cannabinoid receptors and ion channels. CBD also acts through various receptor-independent pathways—for example, by delaying the “reuptake” of endogenous neurotransmitters (such as anandamide and adenosine) and by enhancing or inhibiting the binding action of certain G-protein coupled receptors.

Through this activity, CBD helps people experiencing chronic pain, tremors, mood disorders, sleeplessness, PTSD, inflammation.


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