How Does CBD Work In The ECS?
Because investigation continues into CBD’s effectiveness, we are constantly gaining knowledge.
One significant change in opinion on CBD is whether it binds to cannabinoid receptors. While it used to be believed that CBD binds to CB2 receptors, nowadays things have changed. It appears CBD may heal in an entirely different way.
While this particular information does not affect CBD’s effectiveness, it can change our understanding of exactly how CBD works. This article is going to correct, update, as well as clarify any older posts we have produced on this particular subject. Additionally, we want to give you additional reading if you want to know more.
How Does CBD Work: A Brief Introduction to The ECS And Cannabinoid Receptors
The Endocannabinoid System is a term describing a system in the body that influences many regular functions.
The’ system’ itself has natural compounds your body makes named endocannabinoids. Additionally, it includes several receptors on cells that accept or bind with those endocannabinoids. Lastly, some essential fatty acids and enzymes communicate with endocannabinoids, making them a part of the ECS along with receptors and endocannabinoids.
Some cannabinoids are extremely much like endocannabinoids while others are so close they can bind to ECS receptors (like Anandamide and THC). Still others might not bind to receptors at all. For instance, we now understand that CBD influences the actions of the fatty acids as well as enzymes in the ECS.
How Does CBD Work: THC and Anandamide
Anandamide is a neurotransmitter referred to as the bliss molecule since it encourages happiness as well as a sensation of intoxication. One’s body makes this particular substance all by itself. It binds with your CB1 receptors and science thinks it has a host of wellness effects.
Anandamide is linked to memory, motivation, cognitive processes, coordination, pain, appetite, anxiety, depression, hormones, and even cancer cell development.
When you smoke or eat cannabis, THC binds to the exact same CB1 receptors as Anandamide. This creates ‘high’ and triggers the above advantages too.
Believe it or not, CBD isn’t cannabis and hemp’s only medicinal compound.
How Does CBD Work: Hemp CBD And FAAH
Speaking of CBD, it does not actually bind with CB1 or CB2 receptors. Researchers previously believed CBD did bind to CB2, though the present school of thought rejects this theory. Instead, CBD alters how fast Anandamide breaks down.
Additionally, CBD affects many non-cannabinoid receptors and ion channels as well. Ion channels are membranes which enable ions to pass through them. For example, CBD binds to TRPV1 receptors which mediate pain perception, inflammation as well as body temperature.
CBD also stalls the “reuptake” of endogenous neurotransmitters (such as adenosine and anandamide) and improves or diminishes the binding activity of some G protein coupled receptors.
Additionally, CBD slows FAAH, a fatty acid which breaks down Anandamide.
Yet another CBD effect is triggering the 5 HT1A (hydroxytryptamine) serotonin receptor. More serotonin enhances mood and also decreases anxiety.
How Does CBD Work: Research Continues
It’s important to stay on top of the current research, and we always direct our readers to Project CBD because we believe it is one of the most vital resources the community has. If you haven’t read up on the latest CBD research, follow this link.